Carboxylic acids donate hydrogen ions if a base is present to accept them. Salicylic acid msds rphrases r22 harmful if swallowed. Physical and chemical properties molecular formula 2hoc6h4cooh. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Chemical product and company identification product name. Material safety data sheet acetylsalicylic acid product observe all federal, state, and local environmental regulations. Contact a licensed professional waste disposal service to dispose of this material. It has a role as an antiinfective agent, an antifungal agent, a keratolytic drug, an ec 1. Buy trisalicylic acid cas 85531175, a biochemical for proteomics research, from santa cruz. Out of scope information includes radiopharmaceuticals, contrast media, herbals, homeopathics, and food. Hold eyelids open and flush with a steady, gentle stream of water for at least 15 minutes. California, new jersey, pennsylvania, minnesota, massachusetts. Salicylic acid from latin salix, willow tree is a lipophilic monohydroxybenzoic acid, a type of phenolic acid, and a beta hydroxy acid bha.
Acetylsalicylic acid is hydrolyzed in the plasma to salicylic acid. M21127 section i product and company identification msds name. Laboratory experiments have resulted in mutagenic effects. Sphrases s26 in case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Identification product name salicylic acid usp cat no. Aluminum chloride solutions 20% in sda, 400523, 400763. Salicylic acid is used as a food preservative as well as in the treatment of many skin disorders such as acne, dandruff, psoriasis and seborrheic dermatitis of the skin and scalp. Weve included the most sought after safety data sheets, and the database just keeps growing. Salicylic acid 69727 100 toxicological data on ingredients. Contains the following potentially hazardous materials. It is a common experiment performed in organic chemistry labs, and generally tends to produce low yields due to the relative difficulty of its extraction from an aqueous state.
Seek medical attention if irritation, discomfort, or vomiting persists. Preparation of salicylic acid santa monica college. Most important symptoms and effects, both acute and. Aluminum chloride solutions 40% in 70% sda, 400597. Salicylic acid is lipophilic and has the ability to penetrate into oilfilled follicles and breakdown impaction. Salicylic acid topical for the skin is used in the treatment of acne, dandruff, seborrhea, or psoriasis, and to remove corns, calluses, and warts there are many brands and forms of salicylic acid.
Prevent firefighting water from entering environment. Lowviscosity, slightly yellowlight brown liquid with solventlike odor. Jul 08, 2015 salicylic acid is a colorless crystalline acid derived from organic sources. Emergency telephone no 8668670110 5909 sea lion place, suite h carlsbad, ca 92010 7604483600 section 1. Page 1 of 8 msds phosphoric acid, 85% material safety data sheet msds phosphoric acid, 85% 1. Salicylic acid usp revision date 25jun2019 salicylic acid 891 mgkg rat 2 gkg rat 0. Hazardous in case of skin contact irritant, of eye contact irritant, of ingestion, of inhalation lung irritant. Their reactions with bases, called neutralizations, are accompanied by the evolution of substantial amounts of heat. Betamethasone salicylic acid ointment formulation msds. Composition and information on ingredients composition.
If available, please refer to the product information sheet for application and handling instructions. Clear up spills immediately and dispose of waste safely. In addition to serving as an important active metabolite of aspirin. Search results for salicylic acid msds at sigmaaldrich.
Uses advised against food, drug, pesticide or biocidal product use details of the supplier of the safety data sheet 2. Safety data sheet northwest missouri state university. In case of contact, immediately wash with plenty of soap and water for at least 5 minutes. The product itself and its products of degradation are not toxic. Jun 07, 2019 salicylic acid is a potent skincare ingredient, but how does it work. It is mainly used in the pharmaceutical industry for the manufacture of antipyretic, analgesic, antiinflammatory and diuretic drugs. Collect powder using special dust vacuum cleaner with particle filter or carefully sweep into suitable waste disposal containers and seal securely. It is obtained from the bark of the white willow and wintergreen leaves.
Use water spray or fog for cooling exposed containers. Remove contact lenses, if applicable, and continue flushing. It also functions to normalize the excess interfollicular cell shedding that contributes to the formation of microcomedones. Salicylic acid is also a comedolytic medication because it can break up comedones and open clogged pores. Methyl salicylate is fully degradation biodegradable. According to a classification scheme3, this estimated koc value suggests that salicylic acid is expected to have moderate mobility in soil. Because of its effect on skin cells, salicylic acid is used in several shampoos used to treat dandruff. A correlation was observed between the solubility and the vant hoff enthalpy of solution. Salicylic acid is a key ingredient in many skincare products for the treatment of acne, psoriasis, calluses, corns, keratosis pilaris, and warts. Salicylic acid causes shedding of the outer layer of skin. Radchem cc po box 166982 brackendowns alberton 1454 telephone. Our msds database is an easy to use, do it yourself tool, and best of all. Material safety data sheet west liberty university. Uses advised against food, drug, pesticide or biocidal product use details of the supplier of the safety data.
Salicylic acid allows cells of the epidermis to more readily slough off. California prop 65 the following statement s is are made in order to comply with the california safe drinking water act. Preparation of salicylic acid salicylic acid will be prepared by a basepromoted hydrolysis, or saponi. Hazard identification hazardous in case of skin contact irritant, of eye contact irritant, of ingestion, of inhalation lung irritant. Salicylic acid none listed none listed none listed osha vacated pels. Hazards identification potential acute health effects. Solubility and melting properties of salicylic acid request pdf. This chemical has a variety of applications and can present several health hazards if used without adequate precautions. This chemical is considered hazardous by the 2012 osha hazard.
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Here are some important safety tips to keep in mind when handling and storing salicylic acid. Skin contact in case of skin irritation, discontinue use of product. Material safety data sheet salicylic acid valid for. Material safety data sheet page 1 of 2 salicylic acid. Salicylic acid is a monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. Slightly hazardous in case of skin contact permeator. Salicylic acid acylbdglucuronide methods for cleaning up wear protective clothing as described in section 8 of this safety data sheet. Relevant identified uses of the substance or mixture and uses advised against identified uses laboratory reagent. Bluing reagent methanol bluing reagent scotts substitute chlorazol black e. Dailymed duofilm wart remover salicylic acid liquid. The product will be analyzed by melting point analysis and carbon nmr. Product and company identification product name as on label. Material safety data sheet salicylic acid msds section 1.
Salicylic acid revision 1 revision date 0804 2015 12. Sigmaaldrich 3050 spruce street saint louis mo 63103 usa telephone. Were breaking down how salicylic acid works on the skin, what types of acne it does and doesnt work on, and how best to. Safety data sheet creation date 24nov2009 revision date 25jun2019 revision number 6 1. Call a poison center or doctorphysician if you feel unwell specific treatment see supplemental first aid instructions on this label rinse mouth.
May cause salicylism with effects similar to those of skin absorption. This colorless crystalline organic acid is widely used in organic synthesis and functions as a plant hormone. Matching the most optimal personalized medication with the patients needs is the essence of compounding. Duofilm wart remover salicylic acid liquid out of scope out of scope for rxnorm and will not receive rxnorm normal forms. The melting properties of salicylic acid were determined by differential scanning calorimetry. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Never provide drink or induce vomiting in the event of loss of consciousness. Containers of this material may be hazardous when empty, as they retain product residues. The koc of salicylic acid is estimated as 404src, using a log kow of 2. Severe salicylate intoxication may cause central nervous system disturbances such as convulsions and coma, skin eruptions, and alteration in the acidbase balance. Causes irritation of the mucous membrane and upper respiratory tract. A benzoate ester obtained by the formal condensation of carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol 2hydroxyethyl salicylate preparation products and raw materials raw materials preparation products 2hydroxyethyl.
Whether or not acetaylsalicylic acid aspirin is a human teratogen is controversial. Salicylic acid, when taken orally, is also an analgesic and an antiinflammatory. Your new online msds binder is a place for you to store the material safety data. Salicylic acid which is a naturally occurring substance found in many plants can be acetylated using acetic anhydride, yielding aspirin and acetic acid as a byproduct. More than 200,000 customers have access to over 2,500 highquality pharmaceutical raw materials. Product and company identification salicylic acid synonymsgeneral names. Material safety data sheet salicylic acid section 1 chemical product and company identification msds name. The only beta hydroxy acid typically used in skin care is salicylic acid. Material safety data sheet msds phosphoric acid, 85%. Acetic anhydride safety data sheet according to the federal final rule of hazard communication revised on 2012 hazcom 2012 5. Salicylic acid blocks the production of certain hormones called prostaglandins that are released from damaged cells.
What does salicylic acid do for your skin, exactly. Identification of the substancepreparation and of the company or firm 1. Enter synonyms, trade names or additional information found in section 1. Plasma concentrations of aspirin following after administration of the extendedrelease form are mostly undetectable 48 hours after ingestion of a single dose. Ac158180000, ac158180500, ac158185000, ac385760000 synonyms. State of the art ingredients fast friendly service msds material safety data sheet 512 5352711 unusual fire and explosion hazards. If in scope, these drugs will include rxnorm normal forms when editing is complete. Wear appropriate protective eyeglasses or chemical safety goggles as described by oshas eye and face protection regulations in 29 cfr 1910.
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